![]() ![]() ![]() The synchronized responses are translated into 5 peaks (I–V) (Fig. 5Īuditory stimuli, during the ABR test, are transmitted to the cochlea and evoke neural responses from the auditory nerve up to the upper brainstem. It also serves as an adjunctive tool in assessing the maturation and integrity of the auditory system among infants with normal hearing. In the Neonatal intensive care unit (NICU), the auditory brainstem-evoked responses (ABR) test is primarily used to detect hearing impairment among high-risk infants. 2, 3 Detecting infants at high risk for developmental impairment, who could benefit from early intervention, is highly important and might lead to better outcomes. 1 Magnetic resonance imaging (MRI) studies among premature infants reaching term age revealed abnormal brain maturation, which was correlated with adverse neurodevelopmental outcomes. Premature infants are at higher risk for neurodevelopmental impairment than term infants. The corrected age at ABR testing is of significance, among preterm and term infants. Male sex is significantly associated with prolonged interpeak latencies (IPL) among preterm and term infants, while intraventricular hemorrhage or periventricular leukomalacia, bronchopulmonary dysplasia, and being small for gestation age may be associated with shortened IPL ImpactĪuditory brainstem-evoked response (ABR) test, among normal hearing infants, can serve as a clinical tool to assess brainstem auditory maturation.ĭifferent neurodevelopmental risk factors could have different effects on the maturity of the auditory pathway. ConclusionsĪmong various risk factors for the neurodevelopmental delay, male sex was associated with delayed, while IVH or PVL, BPD and SGA could be associated with accelerated auditory brainstem maturation. Non-invasive mechanical ventilation, did not affect the caudal part of the auditory pathway, despite its high noise level. Multivariable regression analysis revealed that male sex and less advanced PMA at the examination were independent factors associated with prolonged IPL’s, while bronchopulmonary dysplasia, IVH or PVL and being SGA shortened the IPL’s. Sex, PMA at ABR test, being small for gestational age (SGA), intraventricular hemorrhage (IVH) or periventricular leukomalacia (PVL), and days of invasive ventilation were found to significantly affect the IPL’s in the auditory pathway in a univariate analysis. ![]() Interpeak latencies, demographic data, and risk factors were recorded. Retrospective analysis of 239 premature infants (gestational age 32.5 ± 2.1 weeks, birth weight 1827 ± 483 g). We aimed to study the effect of various risk factors for the neurodevelopmental delay on the conduction time in the auditory pathway among normal hearing premature infants, at term postmenstrual age (PMA). Interpeak latencies (IPL), as measured by the auditory brainstem-evoked responses (ABR) test, represent the conduction time, and therefore the maturation of the brainstem auditory pathway. ![]()
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